Cross-Sectional Study - Diversity Outbred (J:DO)
| Project Aims: |
Characterization of healthspan and lifespan in J:DO mice investigating early, mid-life and late life biomarkers of aging. Establishment of a tissue bank to provide aged J:DO resources to the scientific community.
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| Project Start/End Dates: | July 2011 – March 2014 |
| Strain(s): | J:DO (Stock 009376) |
| Quantity/Sex/Age of Animals: |
300 females and 300 males 6, 12, and 18 month timepoints |
| Diet: | 5K52 6% |
| Phenotyping Assays: | Open Field, Novel Object, T-maze, Light/Dark,Tail Suspension, Urinary Incontinence, Urine Analysis, Fecal Analysis, PIXI, Grip and Rotarod. |
| Animal Resources: |
Fat Pad, Muscle, Heart, Liver, Kidney |