Publications

Project Aims:

Characterization of healthspan and lifespan in CC mice investigating early, mid-life and late life biomarkers of aging.
Robust fecal collection, blood collection and phenotyping pipeline.

 
Project Start/End Dates: January 2016 – Ongoing
Strain(s):

CC024/GeniUncJ (AU8004)

CC025/GeniUncJ (AU8008)

CC010/ GeniUncJ (AU8018)

CC026/GeniUncJ (AU8026)

CC042/GeniUncJ (AU8042)

CC051/TauUncJ (IL16912)

CC001/UncJ (OR13140)

CC002/UncJ (OR15156)

CC011/UncJ (OR3252)
Quantity/Sex/Age of animals:

Total: 201 animals in study

8 males and 8 females per cohort per strain.

6, 12, and 18 month timepoints

 
Animal Room

RAF B7 and RAF B8

Temperature: 77o F +/- 2

Link to JAX Animal Room Health Reports
Diet(s):

6% 5KOG

48 hour Fasting or Ad libitum (Control)
Phenotyping Assays: Rotarod, Frailty, Grip, Metabolic Cages
Animal Resources: